MNAzyme-catalyzed nucleic acid detection enhanced by a cationic copolymer
نویسندگان
چکیده
منابع مشابه
MNAzyme-catalyzed nucleic acid detection enhanced by a cationic copolymer.
Multi-component nucleotide acid enzymes (MNAzymes) derived from RNase-mimic DNAzymes have potential as simple and accurate DNA detectors. To enhance the MNAzyme activity under multiple-turnover conditions, a cationic comb-type copolymer, PLL-g-Dex, that facilitates hybridization and strand exchange reactions of DNA was utilized. The copolymer increased the MNAzyme reaction rate by 200 times, al...
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ژورنال
عنوان ژورنال: Biomaterials Science
سال: 2015
ISSN: 2047-4830,2047-4849
DOI: 10.1039/c4bm00449c